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pA major depressive episode may be the initial presentation of bipolar disorderIt is generally believedthough not established in controlled trialsthat treating such an episode with an antidepressant alone may increase the likelihood of precipitation of a mixed/manic episode in patients at risk for bipolar disorderWhether any of the symptoms described above represent such a conversion is unknownHoweverprior to initiating treatment with an antidepressantpatients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disordersuch screening should include a detailed psychiatric historyincluding a family history of suicidebipolar disorderand depressionIt should be noted that REMERONmirtazapineTablets are not approved for use in treating bipolar depression./ppIf you are taking any of these groups of medicationsdiscuss with your doctor how this medication may affect your medical conditionhow your medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed./ppThe effectiveness of REMERON in hospitalized depressed patients has not been adequately studied./ppDo not use Remeron if you have used a MAO inhibitor in the past 14 daysA dangerous drug interaction could occurMAO inhibitors include isocarboxazidlinezolidmethylene blue injectionphenelzinerasagilineselegilinetranylcypromineand others./ppYour doctor may have suggested this medication for conditions other than those listed in these drug information articlesIf you have not discussed this with your doctor or are not sure why you are taking this medicationspeak to your doctorDo not stop taking this medication without consulting your doctor./p
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