Etodolac is used with caution in patients taking blood thinning medications anticoagulants , such as warfarin coumadin , because it increases the risk of bleeding.
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pThis list is not complete and many other drugs can interact with warfarinThis includes prescription and over-the-counter medicinesvitaminsand herbal productsGive a list of all your medicines to any healthcare provider who treats you./ppCOUMADIN has a narrow therapeutic rangeindexand its action may be affected by factors such as other drugs and dietary vitamin KThereforeanticoagulation must be carefully monitored during COUMADIN therapyDetermine the INR daily after the administration of the initial dose until INR results stabilize in the therapeutic rangeAfter stabilizationmaintain dosing within the therapeutic range by performing periodic INRsThe frequency of performing INR should be based on the clinical situation but generally acceptable intervals for INR determinations are 1 to 4 weeksPerform additional INR tests when other warfarin products are interchanged with COUMADINas well as whenever other medications are initiateddiscontinuedor taken irregularlyHeparina common concomitant drugincreases the INRsee Conversion From Other Anticoagulants and DRUG INTERACTIONS/ppAll medicationsincluding warfarinshould always be kept out of the reach of children and pets./ppMany other medicines can interact with COUMADIN and affect the dose you need or increase COUMADIN side effectsDo not change or stop any of your medicines or start any new medicines before you talk to your healthcare provider./p
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consider lower initiation and maintenance doses of coumadin in elderly patients see dosage and administration .
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